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    About once a month a few of us at the office get together during lunch for what has become known as a SWAP meet
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    ing. We share thoughts, stories and sometimes play Pictionary. It’s a great way to relieve stress and learn int
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    eresting tidbits about the people we work with.

    One afternoon our conversation turned, as all conversations ev
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    entually do, to the topic of The Lord of the Rings. Our discussion about differences between the book and the m
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    ovie evolved into a discussion about the characters in the movie which made up the Fellowship of the Ring. The
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    nteresting thing to note was the difference in the levels of awareness of these characters by various people. W
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    e were struck by the similarities in how people remember these movie characters and how people remember certain
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    brands.

    The highest level of character awareness can be called ‘the geek level’. These are people who know th
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    e character's full names as well as additional details about them. For example, knowing that Legolas, Sindarin
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    elf of the woodland realm, is a great archer is comparable to those people who know the brand name, logo and ji
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    gle, all unaided. The next level, still pretty high on the scale, can identify the characters by name and race:
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    Aragorn the human, Gimli the dwarf and Legolas the elf. These are the people who know the brand name and corre
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    ctly match it to the product still without a helping hand. Then there are the people who know the characters by
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    the actors who play them. These people may know the parent company of the brand or the name of the product, bu
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    t don’t know the advertising or what the product actually does.

    After that, the characters become a bit more f
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    zzy. They may be identified by type of being (the dwarf, the elf, the hobbit, etc.) or even worse “the hot guy
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    from The Pirates of the Caribbean movie.” That’s when you know your brand may be in trouble. These people may o
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    nly be aware of your brand when prompted, and may not be at all aware of the advertising or maybe incorrectly i
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    dentify the brand that is being advertised.

    There are varying levels of brand awareness. While we’d all like o
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ur brands to be known on the geek level, realistically they may only be known by association with another brand


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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