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  • Digg It - Using and Converting to Color-Safe Palettes

    When you design web pages in HTML, as you probably know, you can use a tremendous range of colors (over 16 million) for fonts, tables, backgrounds and so forth using the COLOR at
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    tribute of the various HTML tags.

    One thing that many novice webmasters don't think about is whether these colors will be displayed correctly on the screens of visitors who don
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    t have the latest whiz-bang graphics cards.

    There are still people out there who have a graphics cards which are only capable of displaying 256 colors at once. In these cases, t
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    he only colors which you can be sure will be displayed correctly are those in the browser-safe color palette.

    So what happens if your web page includes a color that isn't in the
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    color-safe palette, and a person tries to view on a 256 color screen?

    Answer: It depends on the user's web browser.

    - In some cases, the colors that aren't available will be co
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    nverted to their nearest "color-safe" equivalent. This can lead to your web page looking different from what you intended.

    - In other cases, particularly for large areas of cont
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    nuous color (such as backgrounds and tables), the browser may attempt to simulate the your chosen color by "dithering" two or more color-safe colors together. This usually makes
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    the colors look grainy, and very often looks absolutely terrible. If you don't know what I mean by "dithering", see the explanation at: http://www.graphicsacademy.com/what_dithe
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    .php

    The Solution:

    Review your HTML coding, and look at the colors in each COLOR= attribute... then change them to their closest color-safe equivalents.

    (You might want to mak
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    e a safe copy of your web pages before doing this, in case you make an oopsy).

    Understanding The COLOR Attribute In HTML Code:

    If you look at the COLOR= attributes in the HTML
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    ode, it usually looks something like this

    COLOR="#C20F8C"

    (Sometimes you may also see named colors like "RED" or "MAGENTA" which is beyond the scope of this discussion, just sk
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    p over any of those).

    The values in the quotes after the hash symbol, are actually three pairs of digits, representing the Red, Green, and Blue components of the color expressed
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    as hexadecimal numbers in the range 00 to FF.

    So for the color given above:

    - C2 is the Red component - 0F is the Green component - 8C is the Blue component

    There is also a t
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    ree-digit variant of the above which you may very occasionally run across:

    If you see something like: COLOR="#F9C" Then you simply need to repeat each digit, thus F9C represents
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    :

    - FF for the Red component
    - 99 for the Green component
    - CC for the Blue component


    Converting to Color-Safe Colors:

    Now we understand the theory, we're ready
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    o convert a color to its closest color-safe equivalent.

    For each of the Red, Green and Blue components, you need to convert them separately into values, you need to convert them
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    separately into the color-safe equivalents, and then recombine the whole lot together.

    The conversion step goes like this:

    00 to 19 - converts to 00
    1A to 4C - converts
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    o 33
    4D to 7F - converts to 66
    80 to B2 - converts to 99
    B3 to E5 - converts to CC
    E6 to FF - converts to FF


    For example:

    If we need to convert C20F8C t
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    o its closest color-safe equivalent:

    - We would convert the C2 part to CC
    - We would convert the 0F part to 00
    - We would convert the 8C part to 99
    - And thus we
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ould CC0099 as the final color.


    Some other examples:

    2B2CF0 would convert to 3333FF
    C000C0 would convert to CC00CC
    F0A000 would convert to FF9900
    And so on..


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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    BB link (for phorums):
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