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You’ve probably been hanging out to get stuck into the very nifty Photoshop toolbox. In this article I’ll introduc

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e some of the most frequently used tools found in the toolbox.

You’ll notice that some of the tool icons have sma

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

l black triangles in their bottom right-hand corners. These icons contain hidden treasures! The triangle indicate

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s that there are more related tools available; if you click on the tool icon and hold it down, a “flyout” menu wil

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

appear, displaying the additional tools.

Selection Tools: You can use the selection tools to select certain are

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

s of your document for editing. If you use a selection tool, only the area that’s selected will be affected by any

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

changes you make. You can “feather” selections (specify a fuzzy radius for them) using the Feather field in the o

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

tions bar.

Marquee tools (M) are used to create rectangular or elliptical selections, including selections that a

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

e “single row” (one pixel tall, stretching across the entire width of the document) and “single column” (one pixel

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

wide, tretching through the entire height of the document).

To make single-row or single-column selections, clic

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

with the appropriate tool on the image area where you want to select a row or column. You can use the Lasso tools

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

(L) to create freeform selections.

The Lasso Tool comes in three different forms:

Lasso Tool (L) Click and drag

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

the Lasso Tool to draw a selection area. Releasing the mouse button will close the selection by joining the start

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

nd end points with a straight line.

Polygonal Lasso Tool (L) Click at different points to create vertices of a po

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ygonal shape. Close the selection by moving your cursor to the beginning and clicking once, or pressing the Enter

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

key.

Magnetic Lasso Tool (L) If you think you need help with making your selection, try the Magnetic Lasso Tool.

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

hotoshop will attempt to make a “smart” selection by following the edges of contrast and color difference. Click o

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ce near the “edge” of an object and follow around it—Photoshop will automatically lay down a path.

You can also c

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

lick as you follow the line to force points to be created on the path. Close the selection by pressing the Enter k

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

y or clicking at a point near the beginning of the selection. The Magnetic Lasso Tool is not available in ImageRea

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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