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I spend many hours every day on the internet, and I still find a large number of sites that have a horrible design. There are sites t

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

hat seem to be made for only one resolution, so that if you go there with something other than what the designer thought was the only

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

possible resolution the site looks terrible-images and background skewed off to one side or the other, lines running together in tab

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

les or in a forced attempt at some sort of layout.

Then there are the sites that have no idea what colors go with other colors, and

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

give one a page that has a dark background with dark text, so that it is very difficult to make out what the words are on the page. A

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

nother problem is all of the sites that have an index page with some sort of flash intro movie, but no choice to skip or even any tex

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

t to tell you anything about the site so one can decide if it is worthwhile to sit through the movie.

For people with a broadband co

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

nnection it is only a few seconds (or maybe minutes) before the movie is done, but from listening to people that have dial up connect

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ions it is torture to sit there and wait for 5 to 10 minutes for the movie to download and then to find out it is not something that

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

they wanted to watch in the first place.

Another issue that I have come across is trying to contact a company by way of email, or so

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

metimes by breaking down and using the telephone. Many companies make it so difficult to contact them by way of email, they hide the

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

email address or make one click on so many links to get to a form that must be filled out in order to submit a question that most peo

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ple give up and go away.

There is no reason to make it such an onerous task to contact a company with a question about buying a prod

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

uct or even getting service after buying the product. There is a large company that sells computers and other products that I went to

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

the other day to see about getting a question answered about one of their products that I had purchased some time back. There were

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

so many links to get to where I wanted to be, and then there was a question about a serial number that I did not have the answer to t

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

hat had to be answered before being able to continue. There was a helpful link on the side to recall your number if need be, so I fol

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

lowed that and filled out that form. Lo and behold, I did not exist in the system! A product that I had purchased direct from the man

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ufacturer, and that from the start they had my name, address, credit card number, the whole ball of wax-and I was not in the system!

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

Not to say the least, I was not impressed with this company, and am now doubtful of making another purchase from them in the future!

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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The words hot melt parts may bring to mind the ingredients for one of your favorite deli sandwiches, but in reality, this high speed adhesive technology is used on products that are found in virtually every US household. All around us are products that use hot melt packaging and it is an essential consumer technology.

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