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One thing that is sometimes hard to spot is the person who is advertising for a freelancer but is not really on the up and up. There are a few tips to which ones these might be and I'll cover a few of those

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

here.

The person on a freelance website that says they will not pay for the work but give you a good referral instead. Forget it. This person will take a job that will supposedly only take 5 minut

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s and milk it for as many hours as you will tolerate before quitting. And you get nothing in return except a "good" review. I watched one guy do this and then not even give out top reviews. He would complain

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

about poor communications or not finishing the project etc.

Always check on the previous programmer/designer or whatever because a sure sign that the client is not to be trusted is a lot of prev

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ous freelancers working on the site. One of the things I usually do is ask to speak to the previoius programmer. If it illicits a response of "oh he just took off and I don't know where he is" but the site i

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

90% programmed, warning bells start going off. Or if the programmers did as they are supposed to do and left a log of what work was done on the site and you see quite a few over a short period of time (2 or

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

3 in a year or 2) and the client compains that they just weren't trustworthy or whatever, take a hard look at the situation.

One that I love is the person who advertises saying "I am a programme

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

so I know how long this will take ...." and then says the job will take an experienced programmer only 1/2 hour to do. Well this one should clue you in that s/he is NOT a programmer and is trying to scam yo

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

into a low price. First, if they are good enough to know that it will take "x" number of hours to do it, then they won't tell you. They will wait and see what you come up with and decide if you are trying t

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

o inflate the hours. If they say some silly number like "5 minutes" then they are really clueless. IF they really were a programmer and IF the job was really going to take less than an hour, then it would ha

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

e been faster for them to do it than to go to a website and write an ad and then screen the responses. They DON'T know what they are doing and are trying to intimidate you into a low price. These types will

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

un up the time and if you try and raise the price they will keep on with "I KNOW how long it should have taken and you are OBVIOUSLY not as good as you said you are .... " Putting the blame on you so they ca

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

n refuse to pay more.

The ultra clueless person. Seriously, I have received emails asking if I will clone E-Bay or PayPal or Amazon for $100 or less. Keeping it professional I decline these jobs.

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

Inside I'm saying "are you smoking dope?" This is how I screen a lot of potential jobs. Look at the scope of the job and the top pay they are willing to give you. If it is a LOT of work for little money, the

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

they obviously want to be working with offshore companies that charge $1/hr.

Last but not least and growing in popularity is the "I won't pay until the work is done" scammer. They claim they ha

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ve been ripped off before and so won't pay any money until the work is completed. Then they take it a step further and say the work has to be on their server for a certain amount of time (I've seen up to 30

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

days) before they will pay you. Get real. This is like trying to get a custom built car and driving it for 30 days without making a payment. If you go for this deal you need to just hang your head in sham

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

and get out of the freelancing business totally. INSIST on a deposit or that the full amount be deposited into an escrow account that the client can not close out. Have a signed contract detailing exactly

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

what the acceptance criteria for the project is. INSIST at least on getting some money at the time you turnover the project to them for testing. If you don't do these things, you will never see a dime. <

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

li>

How to protect yourself? First, recognize the situations for what they are. Second of all, always have a contract, and 3rd, if in doubt at all, insist on an escrow account. BUT get that 50% upfront

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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There are many different sales management styles, but which one works the best? Well most experienced practitioners recommend a tough love approach. What is tough love? Well hopefully it is the same type of management your parents and early teachers or sports coaches provided.

A comprehensive series of DXInOne Articles covering various aspects of DXInOne and the DXSystem, from both past, presence and future standpoints.

Discusses the common mistakes of webmasters who don't keep up with the times. Talks about the importancy of monitoring link popularity and submitting every month.

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