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Domain registration is generally very easy. In fact you can simply contact your local domain registrar and give your details like name, address, contact info and of course the

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

name of the domain you want registered and your domain gets registered. Alternatively you can simply go online to your domain registrar’s website and if the facility is provide

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

just fill out a simply online registration form with your name and other details and submit to register your domain. It’s as simple as that.

The problem arrives generally for

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

most of us after the domain has been registered. We keep hearing all these words like name servers, domain pointing and forwarding, domain locking and other things which make i

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

all a nightmare. But it is not as bad as you think. Domain management, once you understand the various aspects to it, is actually a very simply task. We look at some of the as

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ects in domain registration and management which you might have to go through while setting up your website.

Name Servers
Name servers are probably the most common words

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

sed after you have registered a domain. Your hosting company will tell you to change your domain name servers to their address in order for your web hosting service to function

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

properly. So what are name servers?

To put it in simple language, name servers are the name of your server. It basically tells a domain where your website files are located s

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

every time someone types your domain name in their browsers, the domain exactly knows where to go to show your website files – your homepage etc.

Name Servers generally look

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ike this:

Assuming you are hosting with xyz hosting company then your name servers should generally be:

NS1.XYZ.COM
NS2.XYZ.COM

Note the NS could be followed by 3 or 4

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

epending on your hosting company. Your hosting company will generally provide their name servers to you when you register with them.

Domain Forwarding / Domain Redirect
D

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

main forwarding or also know as Domain redirect means if you have multiple domains registered and you want one of your domains to quite simply point to another domain that you

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ave as an active website.

This technique allows you to have a single website be available under multiple domains. For example you can register your domain in both .com and .ne

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

format and then make the .net domain address forward to your .com website. That way you don’t have to spend on having two different websites hosted for each of your domain ext

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ensions.

Domain Locking
This is quite new to the world of domains but is a very important one and you should always be aware of your domain’s status – i.e. whether it is

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ocked or unlocked.

Now, how does domain locking make a difference to you? Firstly if your domain is not locked, then malicious software or hackers have the ability to shift th

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

domain in to their name or shift the domain’s name servers on to their web site which could cause lot of embarrassment to you. Not just that in some cases, hackers can pull th

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

domain from your domain registrar to theirs, giving them full control of your domain.

In general you should always make sure your domain is in locked status. Of course when y

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

u need to change the domain’s name servers etc for your own use then you can unlock a domain. But always make sure moment your work is done and the name servers or any other in

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ormation you are trying to change has been completed, immediately lock your domain. If you can’t lock or unlock your domain, please contact your domain registrar regarding this

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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