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A job offer can reveal a great deal about a prospective employer. It can convey the seriousness of the employer; a candidate’s value to the company and

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

most importantly, the very decision of taking up the offer. It is usually based upon a number of factors out of which only some are flexible. While a

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

actor may be of prime importance to one candidate, it may not be of much significance to another. Here are a few key points to make note of before taki

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ng (or turning down) a job offer:

1. Title And Nature Of The Job
Titles or positions are short but strategic and practical information about the

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ole of a candidate and his/her responsibilities; therefore, it is of prime importance. It is always advisable to be clear on the job role so that one i

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

s certain and mentally ready to accept the new and coveted responsibilities. If in a certain case the job description isn’t explanatory enough, one can

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

keep the option of turning it down (when in doubt).

2. Salary
It would be an educated career move to possess knowledge about industry standards a

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

nd compare the salary offered to the same. Nobody can question the importance of money in life and thus it is an important decision making criteria. A

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

candidate must be sure to ask about the timing of the salary, salary reviews and performance appraisals. Generally, performance reviews are conducted o

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

nce every year or once every six months, depending on the company policy.

3. Bonuses
Bonuses can add a considerable amount to the total pay packa

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

e. It depends upon the company’s relative profit or it can be offered during performance appraisals.

4. Benefits
Benefits or perks add to the bas

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

pay of an employee. Generally, companies offer health and dental insurance through the respective providers. One should find out the facilities and th

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e coverage extended by these providers. Some companies also offer perks or added benefits to some senior executives and managers of the company, inclu

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ing personal perk such as daycare on site, company car, etc. Not all companies offer such perks nor are all employees are entitled to them.

5. Job Loc

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ation
This again is an important piece of information to consider. There’s no point taking up a job where a substantial amount of salary is spent

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ommuting, leave alone the time wasted but also the fatigue due to long hours of travel. You must gauge the factors and see if it is worth relocating or

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

otherwise traveling long distances.

6. Work Culture And Opportunities Offered To An Employee
This again is a subjective case and cannot be answe

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ed with much expertise, as it again varies from person to person, to like or not like the work environment and work culture. While an older person (in

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

a senior position) may not like the open door policy or the culture at work, another middle-aged person, or for that matter, yet another older person m

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

y like this very much. The attitude and aptitude actually differs from person to person so judge what suits you best and make the best decision you can

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Although we are primarily dealing with brands and their optimization, it is important to clarify that brands do not necessarily exist in all markets. Even if brands exist in the legal sense they do not always play a role in the buying decision process of consumers. Other factors may be more important.

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