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Pornography is "hard to to define," but "I know it when I see it," wrote former Supreme Court Justice Potter Stewart in 1964.

Chemistry between two individuals is another gra

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

y area that can be equally difficult to explain. In the context of a job interview, how is it you can have two candidates with comparable backgrounds, experience and skill set

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s: one the client loves while the other they could care less if they ever see again.

You may be thinking, "That's obvious: it's a personality issue"--and I would agree, to an

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

extent. But you don't have to dislike someone's personality to not have chemistry with them. I've interviewed a number of very likable (and capable) people that for whatever

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

eason did not make a favorable impression on the client. I'm always trying to uncover the criteria (experience and skill sets notwithstanding) that the hiring manager is going

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

to use to determine the candidate's suitability for their job.

Psychologist Albert Mehrabian said that 93% of communication is non-verbal--the spoken word only accounts for

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

a mere 7% when delivering a message. I agree that body language and tone of voice are significant factors when it comes to effective communication (and developing chemistry),

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

but I believe the spoken word plays an equally important part. Not just the quality of the message, but the quantity of words used. Let me explain: I recently had the opportun

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ty to participate in a group interview with a client who is hiring for a VP-level position. Since the majority of the companies I work with are outside of South Florida, I don

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

't often get the chance to sit-in on the candidate/client meeting. But after this particular one I think I'm going to start insisting on it because the insight I gained was in

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

valuable.

Interviews with executive-level candidates tend to be more conversational in nature as opposed to rapid-fire Q & A sessions. The participants generally view themsel

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ves as business-equals and most employers recognize that candidates at this level, particularly those recommended by a search firm, are highly qualified and in-demand. It was

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

uring this 90 minute meeting that I watched the chemistry between these two parties begin to develop, then take a dramatic turn downward, only to slowly reignite and begin to

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

build the foundation for a business relationship.

Good conversation should unfold like a tennis match with the two players volleying equally back and forth, not like being sh

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ot at on the other side of the net by a ball machine. When one side either dominates the conversation or doesn't equally contribute with their own thoughts and observations, c

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

hemistry rarely develops. No one likes to be interrogated. An acquaintance of mine is a reporter with a local television station and talking with him is like being on trial fo

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

aggravated homicide: one intensive question after another with him rarely giving any commentary or opinion of his own. Almost as bad is sitting on the receiving side of an "i

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

nformation dump", where the other person goes into mind-numbing detail about topics and issues that are hardly relevant to the discussion.

An interview is but a snapshot of b

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

oth parties involved: it's a first impression to determine whether or not a potential relationship can develop and flourish. Whether you're a hiring manager or job seeker, kee

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

p the "volleying" analogy in the back of your mind during your meeting. Give chemistry every opportunity to develop and you'll find yourself making better employment decisions

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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