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    For many years I managed a computer training centre. During those years I handled the financials, sales and marketing, human resources and anything else that required input. During
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    this time I also on rare occasions and as an emergency, took over in reception answering the phones. This was not difficult and I did a fair job of it. Certainly never had any compl
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    ints! I abided by the easy principle of being friendly to people. I would hazard a guess that I would not be able to find employment as a receptionist as I would not have sufficient
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    work experience.

    What experience would be considered essential to being a good receptionist? I would guess, being able to deal with people would be the most important. Learning how
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    to use the telephone system would require a maximum of half a day's learning, and any clerical systems the company used, would be different from company to company. This means prev
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    ous experience would not count.

    Take this reasoning one step further and apply this to self-employment. If you work for yourself, you will be required to deal with people. Would an
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    wering the telephone at a large company provide you with the experience you need? Or would you be able to learn how to do this by following a few basic steps such as being friendly
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    and helpful. In fact one would almost be inclined to say, that working for a company could mean that you pick up bad habits. Recently I had occasion to phone companies to find out w
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    o the relevant people would be to send information to on training. The general rudeness that I came across during this exercise has been quite staggering. If anybody handling their
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    wn business, were to behave like this to callers, you would be out of business.

    I can hear the objections already. Low skilled jobs are different to high skilled jobs. Working as a
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    investment broker for instance requires work experience. What is experience? It generally involves learning from doing something right or from making mistakes. Some people also lea
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    rn from following people blindly, but those generally tend not to be in senior positions, or if they are, not for very long. Does it matter where this experienced is gained? Workin
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    for yourself you will do things right and you will make mistakes, the same as working for a company. The mistakes you make while working for yourself could be expensive. The mistak
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    s you make for a company could mean you loose your job. There doesn't really seem to me much difference. If you do things right working for yourself you win financially, if you do t
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    hings right for a company, there is generally no change in circumstance. You might get promotion and earn another ?500 per month, or your boss might just take credit for your good w
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    rk!

    In order to minimise making mistakes, we tend to seek advice from other people in the company we work for, whether it is your immediate boss or the division head, or co-worker.
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    When self-employed, finding advice and help is not as easy as walking into the office next door, or asking a co-worker in the cubicle next to you. But help and assistance is availab
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    le as well, and often quicker and cheaper for instance on the internet provided one learns where to find it. Is it quicker in a company? Not necessarily. It requires some time as we
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    l to work out who the right people are to ask, and where the company might keep the resources for additional information.

    I don't really see any huge advantages to working for a co
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    pany when it comes to gaining experience. In fact it can be said that some companies might even teach their staff bad habit such as rudeness to customers or even unethical practices


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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